Washington, March 06 (ANI): A study has indicated that low physical activity increases kidney transplant patients' likelihood of dying early.
The results suggest that patients need to exercise to fend off an early death.
Until now, no one has examined whether low physical activity levels in kidney transplant recipients is associated with an increased risk of dying prematurely from heart-related or other causes. Maintaining heart health is particularly important for these individuals, as kidney transplant recipients have a 4- to 6-fold increased risk of dying from cardiovascular causes than individuals in the general population.
Dorien Zelle (University Medical Center Groningen, in the Netherlands) and her colleagues studied the health of 540 kidney transplant recipients between 2001 and 2003, assessing physical activity through questionnaires and recording deaths until August 2007. With regard to the guidelines for minimum requirements of physical activity, 260 (48 pc) patients did not meet the criteria and 79 (14.6 pc) were completely inactive.
During the study period, 81 patients died, with 37 heart-related deaths; the lower the level of physical activity, the higher the rate of deaths.
Specifically, cardiovascular deaths occurred in 11.7 pc, 7.2 pc, and 1.7 pc of patients considered inactive, moderately active, and active, respectively. Deaths from any cause occurred at rates of 24.4 pc, 15.0 pc, and 5.6 pc in these respective groups.
The investigators acknowledged that in general, sicker people are less likely to exercise and more likely to die; however, they found that the link between low physical activity and premature death was not substantially affected by adjustments for factors such as patients' heart health, kidney function, muscle mass, and their diabetes and smoking status.
The study will be published in an upcoming issue of the Clinical Journal of the American Society Nephrology (CJASN). (ANI)
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