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Scientists develop bones from fat

London, Sun, 10 Jun 2012 NI Wire

Now there is good news in the medical science especially for those who are suffering from any bone related problem. Now researcher has grown a human bone from stem cells taken from fat paving the way for repair or replacement of broken bones with those grown from a patient's own cell. The latest research is certainly a new ray of hope for those patients who have lost their hope for the replacement of their affected bones.

Institute of Research in Israel uses three dimensional scans of the damaged bone to build a gel-like scaffold that matches the shape. The technique could ultimately allow doctors to replace bones that have been smashed in accidents, fill in defects where bone is missing such as cleft palate, or carry out reconstructive plastic surgery.

According to reports an Israeli biotechnology company that has been working with academics on the technology, will be conducting the first patient trial later this year.

Avinoam Kadouri, profoessor and head of the scientific advisory board for Bonus BioGroup, said that there is a need for artificial bones for injuries and in operations. We use three dimensional structures to fabricate the bone in the right shape and geometry. We can grow these bones outside the body and then transplant it to the patient at the right time.

He further added that by scanning the damaged bone area, the implant should fit perfectly and merge with the surrounding tissue. There are no problems with rejection as the cells come from the patient's own body. Stem cells, known as mesenchymal stem cells, which have the capacity to develop into many other types of cell in the body, are obtained from the patient's fat using liposuction.

These are then grown into living bone on the scaffold inside a "bioreactor" - an automated machine that provides the right conditions to encourage the cells to develop into bone.

(With inputs from IANS)


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