Modern day-day-night-night shift pattern less harmful to health, finds study

Washington, Sept 28 (ANI): Previous research has suggested that working in shifts could increase the risk of cancer, although the biological mechanism responsible for this observation is still unknown.

However, a new study has suggested that the modern day-day-night-night shift pattern may not be as disruptive or as potentially carcinogenic as older, more extreme shift patterns.

Melatonin is a hormone that has been shown to have anti-oxidant and tumor suppressor qualities. Since the production of melatonin is tied to the light-dark cycle and peaks between midnight and 4am, shift workers who are exposed to light at night may have an increased risk of diseases like cancer.

Lead author Anne Grundy, a doctoral student in the Department of Community Health and Epidemiology, and her research colleagues recruited 123 female shift workers at Kingston General Hospital (KGH).

They tested the participants to determine both their peak melatonin levels and the overall change in their melatonin levels during a winter day shift and night shift and a summer day shift and night shift.

During these testing periods, the participants wore light meters that objectively measured the surrounding light intensity.

The researchers found that the light level in the KGH wards at night is generally dim and that there is little difference in peak melatonin levels in shift workers working during the day or night shift.

However, in instances where the levels of light increased during a night shift, the workers'overall change in melatonin levels decreased slightly-a finding that is statistically significant.

"Our study indicates that the now common rotating shift pattern of day-day-night-night may not disrupt circadian rhythm or melatonin production significantly," said Grundy.

"We've already seen a shift away from the older patterns of two weeks of days, two weeks of nights, and a short time off to more humane patterns of day-day-night-night then five days off, so it's possible that an intervention to combat the health risks of shift work has already occurred," she said

"However, the overall change in melatonin levels that we found may still be a concern. We look forward to seeing other studies that either confirm our findings or that examine the impact of specific risk factors like extreme shift patterns and higher intensities of light at night," she added.

The findings are published in an online issue of Cancer Epidemiology, Biomarkers and Prevention. (ANI)