Washington, December 8 (ANI): HIV has returned in two patients, who underwent bone marrow transplant to be cured of the virus.
The Boston researcher, Dr. Timothy Henrich, who treated them, said that the HIV virus had become undetectable in both patients approximately eight months after the transplant, but has made a comeback, which is disappointing, but scientifically significant, CNN reported.
The men remained on antiretroviral therapy until the spring of 2013, but the virus became detectable in one patient 12 weeks after ceasing antiretroviral therapy and 32 weeks after antiretroviral therapy ceased in the other.
Henrich said that through this research they have discovered that the HIV reservoir is deeper and more persistent than previously known and that the current standards of probing for HIV may not be sufficient to inform if long-term HIV remission is possible if antiretroviral therapy is stopped.
The research has suggested that there may be an important long-lived HIV reservoir outside the blood compartment. (ANI)
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