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Vitamin C helps reprogram adult cells into stem cells

Washington, Fri, 25 Dec 2009 ANI

Washington, December 25 (ANI): Vitamin C helps boost the reprogramming of adult cells into stem cells, according to a study.

 

Senior study author Dr. Duanqing Pei, South China Institute for Stem Cell Biology and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, and colleagues found that the essential nutrient abundant in citrus fruits enhanced pluripotent stem cells (iPSCs) generation from both mouse and human cells.

 

Experts observed Vitamin C accelerated gene expression changes and promoted a more efficient transition to the fully reprogrammed state.

 

Dr. Pei said: "Our results highlight a simple way to improve iPSC generation and provide additional insight into the mechanistic basis of reprogramming.

 

"It is also of interest that a vitamin with long-suspected anti-aging effects has such a potent influence on reprogramming, which can be considered a reversal of the aging process at the cellular level. It is likely that our work may stimulate further research in this area as well."

 

The study was published online by Cell Press in the journal Cell Stem Cell. (ANI)

 


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