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Higher rifampin can be more effective to fight TB

New Delhi, Jul 02 (ANI): Higher dose of antibiotic called rifampin can kill more tuberculosis bacteria without increasing the adverse effects of treatment. A high enough dose of daily rifampin may reduce the period of the treatment of tuberculosis. Patients who cannot complete the full regimen may not be cured, which permits ongoing transmission and the development of drug-resistant TB. Optimisation of rifampin dosing was considered as a priority because it had the most potent sterilizing effect of the four first-line agents and was available throughout the world. The increased efficacy of higher doses did not appear to result in more grade two or higher rifampin-related adverse events.


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