Sugar helps medicine's battle against chronic bacterial infections

Washington, Thu, 12 May 2011 ANI

Washington, May 12 (ANI): A team of researchers has discovered that a spoonful of sugar not only makes medicine easier to swallow, but it can also help it work.

 

James Collins, a pioneering researcher in the new field of systems biology, is talking about his recent development of an effective, low-cost - and surprising - way to treat chronic bacterial infections, such as staph, strep, tuberculosis, and infections of the urinary tract.

 

He and his team of scientists discovered that a simple compound - sugar - dramatically boosts the effectiveness of first-line antibiotics.

 

Collins' approach consists of adding sugar to the antibiotic. The sugar acts as a stimulant, essentially turning on normal bacterial responses, such as dying when confronted by a killer antibiotic.

 

Using this strategy on E. coli bacteria, a common cause of urinary tract infections, the team was able to eliminate 99.9 per cent of the persisters within just two hours - compared to no effect without sugar.

 

The study has been published in the journal Nature. (ANI)

 



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